1. Yap YG, Camm AJ. Drug induced QT prolongation and torsades de pointes. Heart. 2003. 89:1363–1372. Show 2. Moss AJ, Schwartz PJ, Crampton RS, Tzivoni D, Locati EH, MacCluer J, Hall WJ, Weitkamp L, Vincent GM, Garson A Jr. The long QT syndrome: prospective longitudinal study of 328 families. Circulation. 1991. 84:1136–1144.
3. Fermini B, Fossa AA. The impact of drug-induced QT interval prolongation on drug discovery and development. Nat Rev Drug Discov. 2003. 2:439–447. 4. Woosley RL. Cardiac
actions of antihistamines. Annu Rev Pharmacol Toxicol. 1996. 36:233–252. 5. Yap YG, Camm AJ. The current cardiac safety situation with antihistamines. Clin Exp Allergy. 1999. 29:Suppl 1. 15–24. 6. QT drug lists by risk groups. Arizona Center for Education and Research on Therapeutics. cited 2011 Mar 29. Arizona Center for Education and Research on Therapeutics;Available from:
http://www.azcert.org/medical-pros/drug-lists/drug-lists.cfm. 7. Brown AM. Drugs, hERG and sudden death. Cell Calcium. 2004. 35:543–547. 8. Ahmad SR. Adverse drug event monitoring at the food and drug
administration. J Gen Intern Med. 2003. 18:57–60. 9. Waller PC, Evans SJ. A model for the future conduct of pharmacovigilance. Pharmacoepidemiol Drug Saf. 2003. 12:17–29. 10. Weaver J, Bonnel RA, Karwoski CB, Brinker AD, Beitz J. GI events leading to death in association with celecoxib and rofecoxib. Am J Gastroenterol. 2001. 96:3449–3450. 11. DesRoches CM, Campbell EG, Rao SR, Donelan K, Ferris TG, Jha A, Kaushal R, Levy DE, Rosenbaum S, Shields AE, Blumenthal D. Electronic health
records in ambulatory care: a national survey of physicians. N Engl J Med. 2008. 359:50–60. 12. Park RW, Shin SS, Choi Yl, Ahn JO, Hwang SC. Computerized physician order entry and electronic medical record systems in Korean teaching and general hospitals: results of a 2004 survey. J Am Med Inform Assoc. 2005. 12:642–647. 13. Hauben M, Patadia V, Gerrits C, Walsh L, Reich L. Data mining in pharmacovigilance: the need for a balanced perspective. Drug Saf. 2005. 28:835–842. 14. Dewitt JG, Hampton PM. Development of a data warehouse at an academic health system: knowing a place for the first time. Acad Med. 2005. 80:1019–1025. 15. Zhang Q, Matsumura Y, Teratani T, Yoshimoto S, Mineno T, Nakagawa K, Nagahama M, Kuwata S, Takeda H. The application of an institutional clinical data warehouse to the assessment of adverse drug reactions (ADRs): evaluation of aminoglycoside and cephalosporin associated nephrotoxicity. Methods Inf Med. 2007. 46:516–522. 16. Szirbik NB, Pelletier C, Chaussalet T. Six methodological steps to build medical data warehouses for research. Int J Med Inform. 2006. 75:683–691. 17. Sheen SS, Choi JE,
Park RW, Kim EY, Lee YH, Kang UG. Overdose rate of drugs requiring renal dose adjustment: data analysis of 4 years prescriptions at a tertiary teaching hospital. J Gen Intern Med. 2008. 23:423–428. 18. Hinrichsen VL, Kruskal B, O'Brien MA, Lieu TA, Platt R. Using electronic medical records to enhance detection and reporting of
vaccine adverse events. J Am Med Inform Assoc. 2007. 14:731–735. 19. Akita M, Shibazaki Y, Izumi M, Hiratsuka K, Sakai T, Kurosawa T, Shindo Y. Comparative assessment of prurifloxacin, sparfloxacin, gatifloxacin and levofloxacin in the rabbit model of proarrhythmia. J Toxicol Sci. 2004. 29:63–71. 20. Nykamp DL, Blackmon CL, Schmidt PE, Roberson AG. QTc prolongation associated with combination therapy of levofloxacin, imipramine, and fluoxetine. Ann Pharmacother. 2005. 39:543–546. 21. Gandhi PJ, Menezes PA, Vu HT, Rivera AL, Ramaswamy K. Fluconazole- and levofloxacin-induced torsades de pointes in an intensive care unit patient. Am J Health Syst Pharm. 2003. 60:2479–2483. 22. Taubel J, Naseem A, Harada T, Wang D, Arezina R, Lorch U, Camm AJ. Levofloxacin can be used effectively as a positive control in
thorough QT/QTc studies in healthy volunteers. Br J Clin Pharmacol. 2010. 69:391–400. 23. Tsikouris JP, Peeters MJ, Cox CD, Meyerrose GE, Seifert CF. Effects of three fluoroquinolones on QT analysis after standard treatment courses. Ann Noninvasive Electrocardiol. 2006. 11:52–56. 24. Park MY, Lee YH, Kim EY, Kim WJ, Kam HJ, Choi JP, Han TH, Kang UG, Park RW. A data warehouse based retrospective post-marketing surveillance method: a feasibility test with fluoxetine. J Korean Soc Med Inform. 2009. 15:191–199. 25. Bazett HC. The time relations of the blood-pressure changes after excision of the adrenal glands, with some observations on blood volume changes. J Physiol. 1920. 53:320–339. 26. Viskin S. Long QT syndromes and torsade de pointes. Lancet. 1999. 354:1625–1633. 27. Mattu A, Brady WJ, Perron AD. Electrocardiographic manifestations of
hypothermia. Am J Emerg Med. 2002. 20:314–326. 28. Singh K. Effect of smoking on QT interval, QT dispersion and rate pressure product. Indian Heart J. 2004. 56:140–142. 29. Suzuki M, Nishizaki M, Arita M, Ashikaga T, Yamawake N, Kakuta T, Numano F, Hiraoka M. Increased QT dispersion in patients with vasospastic angina.
Circulation. 1998. 98:435–440. 30. Radhakrishnan M, Agarwal S, Bithal PK, Gupta V. Heparin-induced transient prolongation of the QT interval during endovascular embolisation of intracranial aneurysm. J Clin Neurosci. 2006. 13:489–492. What are examples of health informatics?Q: What are examples of practical applications of health care informatics?. Developing information systems/processes that improve the quality and efficiency of care.. Building, optimizing, and maintaining electronic health record (EHR) systems.. Designing, developing and evaluating emerging technologies.. What are the 3 components of nursing informatics?data, iNforMatioN, KNowledge, aNd wisdoM
Their seminal work provided a definition of nursing informatics and an information management model that identified data, information, and knowledge as key components of NI practice (Figure 2).
Which are examples of public or population health informatics?These include such things as outbreak management, bio-surveillance, disease prevention, and electronic laboratory reporting.
Which examples of informatics and technology are used by health care professionals?A few examples include patient portals, electronic medical records (EMRs), telehealth, healthcare apps, and a variety of data reporting tools including health data analytics and predictive models.
|