1. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: Revised 2015. Global Initiative for Chronic Obstructive Lung Disease (GOLD) [Last accessed on November 2, 2015]. Available at: www.goldcopd.org.
2. Halbert RJ, Natoli JL, Gano A, Badamgarav E, Buist AS, Mannino DM. Global burden of COPD: systematic review and meta-analysis. Eur Respir J. 2006;28:523–32. [PubMed] [Google Scholar]
3. Mannino DM, Buist AS. Global burden of COPD: risk factors, prevalence, and future trends. Lancet. 2007;370:765–73. [PubMed] [Google Scholar]
4. Decramer M, Janssens W, Miravitlles M. Chronic obstructive pulmonary disease. Lancet. 2012;379:1341–51. [PMC free article] [PubMed] [Google Scholar]
5. Vermeeren MA, Creutzberg EC, Schols AM, Postma DS, Pieters WR, Roldaan AC, et al. Prevalence of nutritional depletion in large out-patient population of patients with COPD. Respir Med. 2006;100:1349–55. [PubMed] [Google Scholar]
6. Wagner PD. Possible mechanisms underlying the development of cachexia in COPD. Eur Respir J. 2008;31:492–501. [PubMed] [Google Scholar]
7. Schols AM. Nutrition in chronic obstructive pulmonary disease. Curr Opin Pulm Med. 2000;6:110–5. [PubMed] [Google Scholar]
8. Vestbo J, Prescott E, Almdal T, Dahl M, Nordestgaard BG, Andersen T, et al. Body mass, fat-free body mass, and prognosis in patients with chronic obstructive pulmonary disease from a random population sample: findings from the Copenhagen City Heart Study. Am J Respir Crit Care Med. 2006;173:79–83. [PubMed] [Google Scholar]
9. Scheepers CA, Wouters EF. Body composition and mortality in chronic obstructive pulmonary disease. Am J Clin Nutr. 2005;82:53–9. [PubMed] [Google Scholar]
10. Collins PF, Stratton RJ, Elia M. Nutritional support in chronic obstructive pulmonary disease: A systematic review and meta-analysis. Am J Clin Nutr. 2012;95:1385–95. [PubMed] [Google Scholar]
11. Hallin R, Koivisto-Hursti UK, Lindberg E, Janson C. Nutritional status, dietary energy intake and the risk of exacerbations in patients with chronic obstructive pulmonary disease (COPD) Respir Med. 2006;100:561–7. [PubMed] [Google Scholar]
12. Langen RC, Gosker HR, Remels AH, Schols AM. Triggers and mechanisms of skeletal muscle wasting in chronic obstructive pulmonary disease. Int J Biochem Cell Biol. 2013;45:2245–56. [PubMed] [Google Scholar]
13. Remels AH, Gosker HR, Langen RC, Schols AM. The mechanisms of cachexia underlying muscle dysfunction in COPD. J Appl Physiol (1985) 2013;114:1253–62. [PubMed] [Google Scholar]
14. Schols AM, Fredrix EW, Soeters PB, Westerterp KR, Wouters EF. Resting energy expenditure in patients with chronic obstructive pulmonary disease. Am J Clin Nutr. 1991;54:983–7. [PubMed] [Google Scholar]
15. Grönberg AM, Slinde F, Engström CP, Hulthén L, Larsson S. Dietary problems in patients with severe chronic obstructive disease. J Hum Nutr Diet. 2005;18:445–52. [PubMed] [Google Scholar]
16. Gan WQ, Man SF, Senthilselvan A, Sin DD. Association between chronic obstructive pulmonary disease and systemic inflammation: A systematic review and a meta-analysis. Thorax. 2004;59:574–80. [PMC free article] [PubMed] [Google Scholar]
17. De Godoy I, Donahoe M, Calhoun WJ, Mancino J, Rogers RM. Elevated TNF-α production by peripheral blood monocytes of weight-losing COPD patients. Am J Respir Crit Care Med. 1996;153:633–7. [PubMed] [Google Scholar]
18. Koehler F, Doehner W, Hoernig S, Witt C, Anker SD, John M. Anorexia in chronic obstructive pulmonary disease-association to cachexia and hormonal derangement. Int J Cardiol. 2007;119:83–9. [PubMed] [Google Scholar]
19. Ouchi N, Parker JL, Lugus JJ, Walsh K. Adipokines in inflammation and metabolic disease. Nat Rev Immunol. 2011;11:85–97. [PMC free article] [PubMed] [Google Scholar]
20. Breyer MK, Rutten EP, Locantore NW, Watkins ML, Miller BE, Wouters EF. Dysregulated adipokine metabolism in chronic obstructive pulmonary disease. Nat Rev Immunol. 2011;11:85–97. [Google Scholar]
21. Görek Dilektaşli A, Ulubay G, Bayraktar N, Eminsoy I, Oner Eyüboğlu F. The effects of cachexia and related components on pulmonary functions in patients with COPD. Tuberk Toraks. 2009;57:298–305. [PubMed] [Google Scholar]
22. Barr RG, Bluemke DA, Ahmed FS, Carr JJ, Enright PL, Hoffman EA, et al. Percent emphysema, airflow obstruction, and impaired left ventricular filling. N Engl J Med. 2010;362:217–27. [PMC free article] [PubMed] [Google Scholar]
23. Donahoe M. Nutritional support in advanced lung disease. The pulmonary cachexia syndrome. Clin Chest Med. 1997;18:547–61. [PubMed] [Google Scholar]
24. Balkom van RH, Heijden van der HF, Herwaarden van CL, Dekhuijzen PN. Corticosteroid induced myopathy of the respiratory muscles. Neth J Med. 1994;45:114–22. [PubMed] [Google Scholar]
25. Gosker HR, Wouters EF, van der Vusse GJ, Schols AM. Skeletal muscle dysfunction in chronic obstructive pulmonary disease and chronic heart failure: underlying mechanisms and therapy perspectives. Am J Clin Nutr. 2000;71:1033–47. [PubMed] [Google Scholar]
26. Schols AM, Wouters EF. Nutritional abnormalities and supplementation in chronic obstructive pulmonary disease. Clin Chest Med. 2000;21:753–62. [PubMed] [Google Scholar]
27. Berthon BS, Wood LG. Nutrition and Respiratory Health—Feature Review. Nutrients. 2015;7:1618–43. [PMC free article] [PubMed] [Google Scholar]
28. Ferreira IM, Brooks D, White J, Goldstein R. Nutritional supplementation for stable chronic obstructive pulmonary disease. Cochrane Database Syst Rev. 2012;12:CD000998. [PubMed] [Google Scholar]
29. Cai B, Zhu Y, Ma Yi, Xu Z, Zao Yi, Wang J, Comer GM, et al. Effect of supplementing a high-fat, low-carbohydrate enteral formula in COPD patients. Nutrition. 2003;19:229–32. [PubMed] [Google Scholar]
30. Shaheen SO, Jameson KA, Syddall HE, Aihie Sayer A, Dennison EM, Cooper C, et al. The relationship of dietary patterns with adult lung function and COPD. Eur Respir J. 2010;36:277–84. [PubMed] [Google Scholar]
31. Rawal G, Yadav S, Shokeen P, Nagayach S. Medical nutrition therapy for the critically ill. Int J Health Sci Res. 2015;5:384–93. [Google Scholar]
32. Thies F, Miles EA, Nebe-von-Caron G, Powell JR, Hurst TL, Newsholme EA, et al. Influence of dietary supplementation with long-chain n-3 or n-6 polyunsaturated fatty acids on blood inflammatory cell populations and functions and on plasma soluble adhesion molecules in healthy adults. Lipids. 2001;36:1183–93. [PubMed] [Google Scholar]
33. Persson LJ, Aanerud M, Hiemstra PS, Hardie JA, Bakke PS, Eagan TM. Chronic obstructive pulmonary disease is associated with low levels of vitamin D. PLoS One. 2012;7:e38934. [PMC free article] [PubMed] [Google Scholar]
34. Sundar IK, Hwang JW, Wu S, Sun J, Rahman I. Deletion of vitamin D receptor leads to premature emphysema/COPD by increased matrix metalloproteinases and lymphoid aggregates formation. Biochem Biophys Res Commun. 2011;406:127–33. [PMC free article] [PubMed] [Google Scholar]
35. Rawal G, Yadav S, Shokeen P. Health and the vitamin D. Int J Health Sci Res. 2015;5:416–23. [Google Scholar]
36. Schols AM, Ferreira IM, Franssen FM, Gosker HR, Janssens W, Muscaritoli M, et al. Nutritional assessment and therapy in COPD: a European Respiratory Society statement. Eur Respir J. 2014;44:1504–20. [PubMed] [Google Scholar]