What process stops epidermal cell migration in response to an epidermal injury quizlet?

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Terms in this set (17)

The skin is also known as a (the) _____

cutaneous membrane

Which type of epithelium makes up the epidermis?

keratinized stratified squamous

Which feature(s) of the skin protect(s) us against microbes such as bacteria?
-The many layers of keratinized cells form a barrier against microbes
-Sebum contains compounds which kill bacteria
-Sweat has an acidic pH which suppresses microbial growth
-Langerhans cells can alert the immune system should microbes invade
-All of these are correct

All of these are correct

In addition to a thicker stratum corneum and the presence of a stractum lucidum, the thick skin of the palms and fingertips of the hands and of the soles of the feet have a denser array of sense receptors than skin found elsewhere on the body, and also is hairless.

True

In deep wound healing, an injury has penetrated through to the dermis or even the hypodermis (subcutaneous layer). In this type of wound, the healing process will leave a scar and could involve a loss of some functionality of the area of the wound.

True

Wounds that only damage the epidermis won't bleed because the epidermis is avascular.

True

Although they appear in the dermis, hair follicles are derived from the epidermis

True

Along with sweating, which other responses by skin assists with thermoregulation?

blood vessels near the skin can dilate, increasing blood flow and heat loss

Vitamin D, following acivation in the skin, is converted to the hormone calcitriol by enzymes in the livers and kidneys. People in northern climates who may not get adequate sun exposure can become deficient in Vitamin D. What mineral would be especially affected by this?

calcium

When an epidermal wound begins the healing process, basal cells migrate away from the basement membrane, enlarge, and migrate to fill in the wounded area. As these cells migrate from different sides of the wound, and reach each other, they stop migrating. This process is called _____.

contact inhibition

Formation of granulation tissue and a scab would only happen in deep wound healing where the dermis has been damaged.

True

Which is not true about eccrine/merocrine sweat glands?
-They begin to function at puberty
-They are found throughout the body
-Their excretory duct terminate at the surface of the epidermis
-They regulate body temperature

They begin to function at puberty

Which is the correct sequence of phases for deep wound healing?

inflammation, migration, proliferation, maturation

This type of exocrine gland undergoes a higher rate of mitosis due to its holocrine secretion

sebaceous gland

"Goose bumps" are caused by

contraction of arrector pili muscles

Which statements describing vitamin D are true.
1. The skin produces Vitamin D when exposed to UV light.
2. When the skin is exposed to UV light, it begins the reaction to convert the precursor molecule to calcitriol in the liver than kidneys.
3. Vitamin D supplements can be taken if individuals are not exposed to UV light.
4. Vitamin D stimulates the uptake of calcium from the intestines.
5. Vitamin D inhibits the function of phagocytes in immunity.

2, 3, 4

Which of the following are characteristics of thick skin? Select all that apply.
-Found in the palms, soles of the feet and fingertips
-Does not contain hair follicles
-Contains more sweat glands than thin skin
-Contain epidermal ridges
-Lacking stratum lucidum
-Contains fewer corpuscles of touch than thin skin
-Stratum coreneum has fewer layers in thick than thin.

-Found in the palms, soles of the feet and fingertips
-Does not contain hair follicles
-Contains more sweat glands than thin skin
-Contain epidermal ridges

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What process stops epidermal cell migration in response to epidermal injury?

During wound repair, E-cadherin expression is reduced and alters cell adhesion, promoting cell migration. However, overexpression of E-cadherin makes cells become more tightly packed, thereby preventing cell migration and consequently re-epithelialization [81].

When epidermal cells encounter one another they stop migrating?

When epidermal cells encounter one another, they stop migrating due to a cellular response called contact inhibition. Migration of the epidermal cells stops completely when each is finally in contact with other epidermal cells on all sides.

How does the skin try to repair itself when the epidermis is slightly injured?

Before the basal stem cells of the stratum basale can recreate the epidermis, fibroblasts mobilize and divide rapidly to repair the damaged tissue by collagen deposition, forming granulation tissue. Blood capillaries follow the fibroblasts and help increase blood circulation and oxygen supply to the area.

How does skin respond to injury and repair itself?

When skin is injured, immune cells rush to the site to remove debris, invading pathogens, and dead and damaged skin cells. A blood clot forms over the area, forming a protective scab. Skin cells manufacture new collagen and connective tissue to fill in the wound.